研究業績
【著書・総説 他】
力武 良行. 脳微小血管周囲へのアクアポリン4 の局在に及ぼす血管内皮細胞老化の影響. ファルマシア. 2023年, 59巻8号, p.730-734.
Rikitake Y. Regulation of the SNARE Protein Ykt6 Function by Diprenylation and Phosphorylation. J Biochem. 2022;172(6):337-340.
Tanaka T, Sasaki N, Rikitake Y. Recent advances on the role and therapeutic potential of regulatory T cells in atherosclerosis. J. Clin. Med. 2021,10,5907.
力武 良行. 低分子量G蛋白質の神経系における機能と神経変性疾患との関わり. 脳神経内科. 2021年, 94巻4号, p.460-467.
Rikitake Y. The Apelin/APJ System in the Regulation of Vascular Tone: Friend or Foe? J Biochem. 2021;169(4): 383-386.
佐々木 直人. 制御性T細胞による動脈硬化の予防. 医学のあゆみ. 2019年, 268巻13号, pp.1265-1272.
Amin HZ, Sasaki N, Hirata KI. Regulatory T Cell Immunity in Atherosclerosis. Acta Med Indones. 2017;49(1):63-68.
力武 良行. 細胞の運動と増殖の新規接触阻害機構. 生化学. 2017年, 89巻1号, pp.111-114.
Yamashita T, Emoto T, Sasaki N, Hirata KI. Gut microbiota and coronary artery disease. Int Heart J. 2016;57:663-671.
佐々木 直人，山下 智也，平田 健一. 特集：包括的リスク管理と動脈硬化. 制御性T細胞. 動脈硬化予防. 2016年, 15巻3号, pp.89-91.
Mandai K, Rikitake Y, Mori M, Takai Y. Nectins and nectin-like molecules in development and disease. Curr Top Dev Biol. 2015;112:197-231.
力武 良行. 特集：新しい循環器病のバイオマーカー-臨床的意義を理解する-「接着分子」. Heart View. 2015年11月増刊号, pp.154-157.
Sasaki N, Yamashita T, Kasahara K, Takeda M, Hirata K. Regulatory T cells and tolerogenic dendritic cells as critical immune modulators in atherogenesis. Curr Pharm Des. 2015;21:1107-1117.
Yamashita T, Sasaki N, Kasahara K, Hirata K. Anti-inflammatory and immune-modulatory therapies for preventing atherosclerotic cardiovascular disease. J Cardiol. 2015;66(1):1-8.
Yamashita T, Kasahara K, Emoto T, Matsumoto T, Mizoguchi T, Kitano N, Sasaki N, Hirata K. Intestinal immunity and gut microbiota as therapeutic targets for preventing atherosclerotic cardiovascular diseases. Circ J. 2015;79:1882-1890.
Mori M, Rikitake Y, Mandai K, Takai Y. Roles of nectins and nectin-like molecules in the nervous system. Adv Neurobiol. 2014;8:91-116.
【論文】
(2025)
1. Uenoyama K, Onoue M, Katayama T, Makihara K, Yamamoto H, Takagi M, Omoto K, Rikitake Y. Administration of immune checkpoint inhibitors to patients on warfarin may elevate PT-INR. YAKUGAKU ZASSHI. 2025;145:71-78.
2. Tanaka T, Sasaki N, Krisnanda A, Amin H.Z, Itoh K, Horibe S, Matsuo K, Hirata KI, Nakayama T, Rikitake Y. C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice. eLife. in press.
(2024)
1. Horibe S, Emoto T, Mizoguchi T, Tanaka T, Kawauchi S, Sasaki N, Yamashita T, Ikeda K, Emoto N, Hirata KI, Rikitake Y. Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease. Glia. 2024;72:51–68.
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2. Tanaka T, Sasaki N, Krisnanda A, Shinohara M, Amin H.Z, Horibe S, Itoh K, Iwaya M, Fukunaga A, Hirata KI, Rikitake Y. A novel ultraviolet B phototherapy with a light-emitting diode device prevents atherosclerosis by augmenting regulatory T cell responses in mice. J Am Heart Assoc. 2024;13(2):e031639.
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3. Takeda S, Emoto T, Yamashita T, Yamamoto H, Takaya T, Sawada T, Yoshida T, Inoue M, Suzuki Y, Hamana T, Inoue T, Taniguchi M, Sasaki N, Otake H, Ohkawa T, Furuyashiki T, Kawai H, Hirata KI. Single-cell RNA sequencing reveals an immune landscape of CD4+ T cells in coronary culprit plaques with acute coronary syndrome in humans-Brief Report. Arterioscler Thromb Vasc Biol. 2024;44(5):1135-1143.
4. Krisnanda A, Sasaki N, Itoh K, Tanaka T, Shinohara M, Amin H.Z, Horibe S, Iwaya M, Hirata KI, Fukunaga A, Rikitake Y. 312 nm UVB phototherapy limits atherosclerosis by regulating immunoinflammatory responses in mice. Kobe J Med Sci. 2024;70(4):E130-E142.
5. Makihara K, Habu Y, Ishihara Y, Goto E, Yoshino S, Mioki D, Ejima T, Mimatsu S, Rikitake Y, Miyata O. Effect of Fentanyl Coadministration on the Prothrombin Time-International Normalized Ratio in Patients Receiving Warfarin: A Multicenter Retrospective Observational Study. 日本緩和医療薬学雑誌．2024;17(1):1-7.
(2023)
1. Kawauchi S, Mizoguchi T, Horibe S, Tanaka T, Sasaki N, Ikeda K, Emoto N, Hirata KI, Rikitake Y. Gliovascular interface abnormality in mice with endothelial cell senescence. Glia. 2023;71:467-479.
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2. Goto E, Hata T, Nishihara M, Neo M, Iwamoto M, Kimura K, Goto M, Rikitake Y. Preventive effects of dexamethasone premedication on the development of infusion-related reactions in breast cancer patients receiving trastuzumab. Br J Clin Pharmacol. 2023;89:2102–2112.
3. Shima Y, Sasagawa S, Ota N, Oyama R, Tanaka M, Kubota-Sakashita M, Kawakami H, Kobayashi M, Takubo N, Ozeki AN, Sun X, Kim YJ, Kamatani Y, Matsuda K, Maejima K, Fujita M, Noda K, Kamiyama H, Tanikawa R, Nagane M, Shibahara J, Tanaka T, Rikitake Y, Mataga N, Takahashi S, Kosaki K, Okano H, Furihata T, Nakaki R, Akimitsu N, Wada Y, Ohtsuka T, Kurihara H, Kamiguchi H, Okabe S, Nakafuku M, Kato T, Nakagawa H, Saito N, Nakatomi H. Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms. Sci Transl Med. 2023; 15(700): eabq7721.
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4. Munekane, M, Mori H, Takada N, Sano K, Yamasaki T, Tanaka T, Sasaki N, Rikitake Y, Mukai T. Preparation and evaluation of 111In-labeled liposomes containing phosphatidylglycerol for detection of macrophages in atherosclerotic plaques. Nucl Med Biol. 2023;126-127:108388.
(2022)
1. Horibe S, Ishikawa K, Nakada K, Wake M, Takeda N, Tanaka T, Kawauchi S, Sasaki N, Rikitake Y. Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells. Oncol Rep. 2022;47(3):32.
2. Emoto T, Yamamoto H, Yamashita T, Takaya T, Sawada T, Takeda S, Taniguchi M, Sasaki N, Yoshida N, Saito Y, Sivasubramaniyam T, Otake H, Furuyashiki T, Robbins CS, Kawai H, Hirata KI. Single-Cell RNA Sequencing Reveals a Distinct Immune Landscape of Myeloid Cells in Coronary Culprit Plaques Causing Acute Coronary Syndrome. Circulation. 2022;145(18):1434-1436.
3. Kasahara K, Sasaki N, Amin HZ, Tanaka T, Horibe S, Yamashita T, Hirata KI, Rikitake Y. Depletion of Foxp3+ regulatory T cells augments CD4+ T cell immune responses in atherosclerosis-prone hypercholesterolemic mice. Heliyon. 2022;8(7):e09981.
(2021)
1. Adhikara IM, Yagi K, Mayasari DS, Suzuki Y, Ikeda K, Ryanto GRT, Sasaki N, Rikitake Y, Nadanaka S, Kitagawa H, Miyata O, Igarashi M, Hirata KI, Emoto N. Chondroitin Sulfate N-acetylgalactosaminyltransferase-2 Impacts Foam Cell Formation and Atherosclerosis by Altering Macrophage Glycosaminoglycan Chain. Arterioscler Thromb Vasc Biol. 2021;41(3):1076-1091.
2. Harada Y, Tanaka T, Arai Y, Isomoto Y, Nakano A, Nakao S, Urasaki A, Watanabe Y, Kawamura T, Nakagawa O. ETS-dependent enhancers for endothelial-specific expression of serum/glucocorticoid-regulated kinase 1 during mouse embryo development. Genes Cells. 2021;26(8):611-626.
3. 六車 龍介，村井 潤，大塚 章人，力武 良行. 2型糖尿病患者におけるカルシウム、リン及びマグネシウム動態に及ぼすSGLT2阻害薬の影響. くすりと糖尿病. 2021;10(2):209.
(2020)
1. Barinda AJ, Ikeda K, Nugroho DB, Wardhana DA, Sasaki N, Honda S, Urata R, Matoba S, Hirata KI, Emoto N. Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype. Nat Commun. 2020;11(1):481.
2. Amin HZ, Sasaki N, Hirata K, Rikitake Y. Cytotoxic T-lymphocyte–Associated Antigen-4 Protects against Angiotensin II-Induced Kidney Injury in Mice. Circ Rep. 2020;2(6):339-342.
3. Goto E, Yamaguchi T, Hattori N, Goto M, Nishuhara M, Uchiyama K, Rikitake Y. Safety of Ramucirumab Regimen without H1-antihistamine Premedication in Patients with Solid Cancers. In Vivo. 2020;34(6):3489-3493.
(2019)
1. Kawauchi S, Horibe S, Sasaki N, Hirata K, Rikitake Y. A novel in vitro co-culture model to assess contact formation between astrocytic processes and cerebral vessels. Exp Cell Res. 2019;374(2019):333–341.
2. Kawauchi S, Horibe S, Sasaki N, Tanahashi T, Mizuno S, Hamaguchi T, Rikitake Y. Inhibitory effects of sodium alginate on hepatic steatosis in mice induced by a methionine- and choline-deficient diet. Mar Drugs. 2019;17(2):104.
3. Emoto T, Sasaki N, Yamashita T, Fukunaga A, Masaki T, Nishigori C, Hirata K. Possible beneficial effects of narrow-band UVB therapy on hypertension and vitamin D levels in patients with cutaneous disease. Photomed Photobiol. 2019;40:17-22.
4. Amin HZ, Sasaki N, Yamashita T, Mizoguchi T, Hayashi T, Emoto T, Matsumoto T, Yoshida N, Tabata T, Horibe S, Kawauchi S, Rikitake Y, Hirata KI. CTLA-4 protects against angiotensin II-Induced abdominal aortic aneurysm formation in mice. Sci Rep. 2019;9:8065.
5. Sekimoto H, Rikitake Y. Efficacy and safety of levetiracetam in Japanese epilepsy patients: A retrospective cohort study. J Clin Pharm Ther. 2019;44:912–923.
6. Noguchi YT, Nakamura M, Hino N, Nogami J, Tsuji S, Sato T, Zhang L, Tsujikawa K, Tanaka T, Izawa K, Okada Y, Doi T, Kokubo H, Harada A, Uezumi A, Gessler M, Ohkawa Y, Fukada SI. Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires Hes1 to bind diverse DNA sites. Development. 146(4), 2019.
7. Shirakura K, Ishiba R, Kashio T, Funatsu R, Tanaka T, Fukada SI, Ishimoto K, Hino N, Kondoh M, Ago Y, Fujio Y, Yano K, Doi T, Aird WC, Okada Y. The Robo4-TRAF7 complex suppresses endothelial hyperpermeability in inflammation. J Cell Sci. 132(1), 2019.
(2018)
1. Horibe S, Tanahashi T, Kawauchi S, Yasuike S, Murakami Y, Rikitake Y. Mechanism of recipient cell-dependent differences in exosome uptake. BMC Cancer. 2018;18:47.
2. Yoshida N, Emoto T, Yamashita T, Watanabe H, Hayashi T, Tabata T, Ozawa G, Hoshi N, Hatano N, Sasaki N, Mizoguchi T, Amin HZ, Hirota Y, Ogawa W, Yamada T, Hirata K. Bacteroides vulgatus and Bacteroides dorei Reduce Gut Microbial Lipopolysaccharide Production and Inhibit Atherosclerosis. Circulation. 2018;138(22):2486-2498.
3. Hayashi T, Yamashita T, Watanabe H, Kami K, Yoshida N, Tabata T, Emoto T, Sasaki N, Mizoguchi T, Irino Y, Toh R, Shinohara M, Okada Y, Ogawa W, Yamada T, Hirata KI. Gut Microbiome and Plasma Microbiome-Related Metabolites in Patients with Decompensated and Compensated Heart Failure. Circ J. 2018;83(1):182-192.
4. Yamamoto H, Yoshida N, Shinke T, Otake H, Kuroda M, Sakaguchi K, Hirota Y, Toba T, Takahashi H, Terashita D, Uzu K, Tahara N, Shinkura Y, Kuroda K, Nagasawa Y, Nagano Y, Tsukiyama Y, Yanaka KI, Emoto T, Sasaki N, Yamashita T, Ogawa W, Hirata KI. Impact of CD14++CD16+ monocytes on coronary plaque vulnerability assessed by optical coherence tomography in coronary artery disease patients. Atherosclerosis. 2018;269:245-251.
5. Yamamoto H, Yoshida N, Shinke T, Otake H, Kuroda M, Sakaguchi K, Hirota Y, Toba T, Takahashi H, Terashita D, Uzu K, Tahara N, Shinkura Y, Kuroda K, Nagasawa Y, Nagano Y, Tsukiyama Y, Yanaka KI, Emoto T, Sasaki N, Yamashita T, Ogawa W, Hirata KI. Data on impact of monocytes and glucose fluctuation on plaque vulnerability in patients with coronary artery disease. Data Brief. 2018;18:172-175.
6. Tagashira T, Fukuda T, Miyata M, Nakamura K, Fujita H, Takai T, Hirata K, Rikitake Y. Afadin facilitates VEGF-induced network formation and migration of vascular endothelial cells by inactivating ROCK through ArhGAP29. Arterioscler Thromb Vasc Biol. 2018;38:1159-1169.
7. Sato J, Horibe S, Kawauchi S, Sasaki N, Hirata K, Rikitake Y. Involvement of aquaporin-4 in laminin-enhanced process formation of mouse astrocytes in 2D culture: Roles of dystroglycan and α-syntrophin in the expression of aquaporin-4. J Neurochem. 2018;147(4):495-513.
Editorial: Towards a better understanding of AQP4′s role in astrocytic process extension.
8. Horibe S, Kawauchi S, Tanahashi T, Sasaki N, Mizuno S, Rikitake Y. CD44v-dependent upregulation of xCT is involved in the acquisition of cisplatin-resistance in human lung cancer A549 cells. Biochem Biophys Res Commun. 2018;507(1-4):426-432.
9. 上田 久美子，寺岡 麗子，八巻 耕也，土生 康司，宮田 興子，力武 良行，中山 尋量，北河 修治. チーム基盤型学習を用いた分野横断統合演習の構築の試み その3 ―臨床系教員との連携ならびにRAT問題を踏まえた応用演習課題の作成―. 神戸薬科大学研究論集Libra. 第18号, pp.29-44.
(2017)
1. Sasaki N, Yamashita T, Kasahara K, Fukunaga A, Yamaguchi T, Emoto T, Yodoi K, Matsumoto T, Nakajima K, Kita T, Takeda M, Mizoguchi T, Hayashi T, Sasaki Y, Hatakeyama M, Taguchi K, Washio K, Sakaguchi S, Malissen B, Nishigori C, Hirata K. Ultraviolet B exposure prevents atherosclerosis by regulating immuno-inflammatory responses. Arterioscler Thromb Vasc Biol. 2017;37(1):66-74.
2. Emoto T, Yamashita T, Kobayashi T, Sasaki N, Hirota Y, Hayashi T, So A, Kasahara K, Yodoi K, Matsumoto T, Mizoguchi T, Ogawa W, Hirata KI. Characterization of gut microbiota profiles in coronary artery disease patients using data mining analysis of terminal restriction fragment length polymorphism: gut microbiota could be a diagnostic marker of coronary artery disease. Heart Vessels. 2017;32(1):39-46.
3. Suzuki A, Fukuzawa K, Yamashita T, Yoshida A, Sasaki N, Emoto T, Takei A, Fujiwara R, Nakanishi T, Yamashita S, Matsumoto A, Konishi H, Ichibori H, Hirata K. Circulating intermediate CD14++CD16+ monocytes are increased in patients with atrial fibrillation and reflect the functional remodelling of the left atrium. Europace. 2017;19(1):40-47.
4. Kasahara K, Tanoue T, Yamashita T, Yodoi K, Matsumoto T, Emoto T, Mizoguchi T, Hayashi T, Kitano N, Sasaki N, Atarashi K, Honda K, Hirata KI. Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis. J Lipid Res. 2017;58(3):519-528.
5. Terao Y, Fujita H, Horibe S, Sato J, Minami S, Kobayashi M, Matsuoka I, Sasaki N, Satomi-Kobayashi S, Hirata K, Rikitake Y. Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion. Biochem Biophys Res Commun. 2017;486:811-816.
6. Mizoguchi T, Kasahara K, Yamashita T, Sasaki N, Yodoi K, Matsumoto T, Emoto T, Hayashi T, Kitano N, Yoshida N, Amin HZ, Hirata KI. Oral administration of the lactic acid bacterium Pediococcus acidilactici attenuates atherosclerosis in mice by inducing tolerogenic dendritic cells. Heart Vessels. 2017;32(6): 768-776.
7. Horibe S, Kawauchi S, Yasuike S, Mizuno S, Kato I, Rikitake Y. Anti-inflammatory effect of JBP485 on dextran dulfate dodium-induced colitis in mice. J Biomed. 2017;2(2):101-108.
8. Yamana S, Tokiyama A, Fujita H, Terao Y, Horibe S, Sasaki N, Satomi-Kobayashi S, Hirata K, Rikitake Y. Necl-4 enhances the PLCγ–c-Raf–MEK–ERK pathway without affecting internalization of VEGFR2. Biochem Biophys Res Commun. 2017;490:169-175.
9. Kawashima T, Takito J, Shimada Y, Sato M, Inoue M, Miyazaki T, Miyata M, Rikitake Y, Takai Y, Nakamura M. Dynamic expression of nectins in enamel organs of mouse incisors. J Oral Biosci. 2017;59:172-178.
10. Hayashi T, Sasaki N, Yamashita T, Mizoguchi T, Emoto T, Amin H. Z, Yodoi K, Matsumoto T, Kasahara K, Yoshida N, Tabata T, Kitano N, Fukunaga A, Nishigori C, Rikitake Y, Hirata K. UVB exposure inhibits angiotensin II-Induced abdominal aortic aneurysm formation in mice by expanding CD4+Foxp3+ regulatory T cells. J Am Heart Assoc. 2017;6(9).
11. Yoshida N, Yamamoto H, Shinke T, Otake H, Kuroda M, Terashita D, Takahashi H, Sakaguchi K, Hirota Y, Emoto T, Amin HZ, Mizoguchi T, Hayashi T, Sasaki N, Yamashita T, Ogawa W, Hirata KI. Impact of CD14++CD16+ monocytes on plaque vulnerability in diabetic and non-diabetic patients with asymptomatic coronary artery disease: a cross-sectional study. Cardiovasc Diabetol. 2017;16(1):96.
12. Toba T, Mori S, Yatani A, Sugisaki Y, Akita T, Sasaki N, Otake H, Shinke T, Mori H, Nishii T, Kono AK, Hirata KI. Spontaneous coronary artery intramural hematoma in a patient with vascular Ehlers-Danlos syndrome: Serial findings in coronary computed tomographic angiography. J Cardiovasc Comput Tomogr. 2017;11(4):324-326.
(2016)
1. Horibe S, Tanahashi T, Kawauchi S, Mizuno S, Rikitake Y. Preventative effects of sodium alginate on indomethacin-induced small-intestinal injury in mice. Int. J. Med. Sci. 2016;13:653-663.
2. Miyata M, Mandai K, Maruo T, Sato J, Shiotani H, Kaito A, Itoh Y, Wang S, Fujiwara T, Mizoguchi A, Takai Y, Rikitake Y. Localization of nectin-2δ at perivascular astrocytic endfoot processes and degeneration of astrocytes and neurons in nectin-2 knockout mouse brain. Brain Res. 2016;1649(Pt A):90-101.
3. Kawauchi S, Nakamura T, Horibe S, Tanahashi T, Mizuno S, Hamaguchi T, Rikitake Y. Mechanism of changes in hepatic CYP3A expression in a rat model of indomethacin-induced small intestinal ulcers. Biopharm Drug Dispos. 2016;37:522-532.
4. Matsumoto T, Sasaki N, Yamashita T, Emoto T, Kasahara K, Mizoguchi T, Hayashi T, Yodoi K, Kitano N, Saito T, Yamaguchi T, Hirata K. Overexpression of CTLA-4 prevents atherosclerosis in mice. Arterioscler Thromb Vasc Biol. 2016;36:1141-1151.
5. Emoto T, Yamashita T, Sasaki N, Hirota Y, Hayashi T, So A, Kasahara K, Yodoi K, Matsumoto T, Mizoguchi T, Ogawa W, Hirata K. Analysis of gut microbiota in coronary artery disease patients: a possible link between gut microbiota and coronary artery disease. J Atheroscler Thromb. 2016;23:908-921.
6. Yamanaka K, Sasaki N, Fujita Y, Kawamoto A, Hirata KI, Okita Y. Impact of acquired and innate immunity on spinal cord ischemia and reperfusion injury. Gen Thorac Cardiovasc Surg. 2016;64:251-259.
7. Tamori A, Murakami Y, Kubo S, Itami S, Uchida-Kobayashi S, Morikawa H, Enomoto M, Takemura S, Tanahashi T, Taguchi YH, Kawada N. MicroRNA expression in hepatocellular carcinoma after the eradication of chronic hepatitis virus C infection using interferon therapy. Hepatol Res. 2016;46(3):E26-35.
(2015)
1. Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y. The cell adhesion molecule Necl-4/CADM4 serves as a novel regulator for contact inhibition of cell movement and proliferation. PLoS One. 2015;10(4):e0124259.
2. Terao Y, Satomi-Kobayashi S, Hirata K, Rikitake Y. Involvement of Rho-associated protein kinase (ROCK) and bone morphogenetic protein-binding endothelial cell precursor-derived regulator (BMPER) in high glucose-increased alkaline phosphatase expression and activity in human coronary artery smooth muscle cells. Cardiovasc Diabetol. 2015;14:104.
3. Mori S, Takaya T, Kinugasa M, Ito T, Takamine S, Fujiwara S, Nishii T, Kono A, Inoue T, Satomi-Kobayashi S, Rikitake Y, Okita Y, Hirata K. Three-dimensional quantification and visualization of aortic calcification by multidetector-row computed tomography: A simple approach using a volume-rendering method. Atherosclerosis. 2015;239(2):622-628.
4. Kondo K, Ishida T, Yasuda T, Nakajima H, Mori K, Tanaka N, Mori T, Monguchi T, Shinohara M, Irino Y, Toh R, Rikitake Y, Kiyomizu K, Tomiyama Y, Yamamoto J, Hirata K. Trans-fatty acid promotes thrombus formation in mice by aggravating antithrombogenic endothelial functions via Toll-like receptors. Mol. Nutr. Food Res. 2015;59(4):729-740.
5. Inoue T, Fujiwara T, Rikitake Y, Maruo T, Mandai K, Kimura K, Kayahara T, Wang S, Itoh Y, Sai K, Mori M, Mori K, Mizoguchi A, Takai Y. Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb. J Comp Neurol. 2015; 523(12):1824-1839.
6. Fujiwara T, Inoue T, Maruo T, Rikitake Y, Nao Ieki, Mandai K, Kimura K, Kayahara T, Wang S, Itoh Y, Sai K, Mori M, Mori K, Takai Y, Mizoguchi A. Nectin-1 spots at contacts between mitral cell dendrites regulate their branching in the mouse olfactory bulb corresponding. Mol Cell Neurosci. 2015;68:143-150.
7. Yamani LN, Yano Y, Utsumi T, Juniastuti, Wandono H, Widjanarko D, Triantanoe A, Wasityastuti W, Liang Y, Okada R, Tanahashi T, Murakami Y, Azuma T, Soetjipto, Lusida MI, Hayashi Y. Ultra-deep Sequencing to Detect Quasispecies Variants in the Major Hydrophilic Region of Hepatitis B Virus in Indonesian Patients. J Clin Microbiol. 2015;53(10):3165-3175.
8. Hayakawa M, Umeyama H, Iwadate M, Tanahashi T, Yano Y, Enomoto M, Tamori A, Kawada N, Murakami Y. Development of novel hepatitis B virus capsid inhibitor using in silico screening. Biochem Biophys Res Commun. 2015;463(4):1165-1175.
9. Horibe S, Matsuda A, Tanahashi T, Inoue J, Kawauchi S, Mizuno S, Ueno M, Takahashi K, Maeda Y, Maegouchi T, Murakami Y, Yumoto R, Nagai J, Takano M. Cisplatin resistance in human lung cancer cells is linked with dysregulation of cell cycle associated proteins. Life Sci. 2015;124:31-40.
10. Murakami Y, Hayakawa M, Yano Y, Tanahashi T, Enomoto M, Tamori A, Kawada N, Iwadate M, Umeyama H. Discovering novel direct acting antiviral agents for HBV using in silico screening. Biochem Biophys Res Commun. 2015;456(1):20-8.
11. Yodoi K, Yamashita T, Sasaki N, Kasahara K, Emoto T, Matsumoto T, Kita T, Sasaki Y, Mizoguchi T, Sparwasser T, Hirata K. Foxp3+ regulatory T cells play a protective role in angiotensin II-induced aortic aneurysm formation in mice. Hypertension. 2015;65:889-895.
(2014)
1. Fukuda T, Kominami K, Wang S, Togashi H, Hirata KI, Rikitake Y, Takai Y. Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities. Development. 2014;141(2):399-409.
2. Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox AJ, Asada Y, Wierman ME, Hirata K, Rikitake Y. Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: Implication in vascular inflammation. PLoS One. 2014;9(9):e107236.
3. Kobayashi R, Kurita S, Miyata M, Maruo T, Mandai K, Rikitake Y, Takai Y. s-Afadin binds more preferentially to the cell adhesion molecules nectins than l-afadin. Genes Cells. 2014;19(12):853-863.
4. Kawauchi S, Nakamura T, Yasui H, Nishikawa C, Miki I, Inoue J, Horibe S, Hamaguchi T, Tanahashi T, Mizuno S. Intestinal and hepatic expression of cytochrome P450s and mdr1a in rats with indomethacin-induced small intestinal ulcers. Int J Med Sci. 2014;11(12):1208-17.
5. Murakami Y, Tanahashi T, Okada R, Toyoda H, Kumada T, Enomoto M, Tamori A, Kawada N, Taguchi YH, Azuma T. Comparison of Hepatocellular Carcinoma miRNA Expression Profiling as Evaluated by Next Generation Sequencing and Microarray. PLoS One. 2014;9(9):e106314.
6. Iwamoto A, Tanahashi T, Okada R, Yoshida Y, Kikuchi K, Keida Y, Murakami Y, Yang L, Yamamoto K, Nishiumi S, Yoshida M, Azuma T. Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes. Gut Pathog. 2014;6:27.
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